Astros ace Justin Verlander has been placed on the 15-day IL with a calf injury.
Verlander injured the leg in Sunday’s win over Baltimore.
The Cy Young frontrunner is 16-3 with a 1.84 ERA in 152 innings pitched.
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Houston picked up the slack in his absence Tuesday night, edging the Texas Rangers, 4-2.
Framber Valdez was stellar on the mound, allowing just two runs in eight innings of work.
The two teams wrap up their Lone Star series Wednesday afternoon at 1:05 p.m.
Coverage is on Zone 1150 AM & 93.7 FM.